Aspirin substitute is a drug known as clopidogrel, sometimes called ‘super aspirin’. It acts by a different mechanism and can be given to those intolerant to aspirin. It can also be combined with aspirin as dual anti-platelet therapy. In some countries, cilostazol is also used for its anti-platelet action. The combination of aspirin, clopidogrel and cilostazol has been called triple anti-platelet therapy.