Amiodarone increases the serum concentration of digoxin by decreasing both renal and nonrenal clearance of digoxin. Hence the dose of digoxin may have to be reduced when amiodarone is added.
Amiodarone increases the serum concentration of digoxin by decreasing both renal and nonrenal clearance of digoxin. Hence the dose of digoxin may have to be reduced when amiodarone is added.
