http://www.cardiophile.com Live life heart healthy! Sun, 21 Feb 2010 09:16:04 +0000 http://wordpress.org/?v=2.9.2 en hourly 1 http://www.cardiophile.com http://www.cardiophile.pgblazer.com/favicon.ico http://www.cardiophile.com/2009/09/how-does-mannitol-cause-transient-volume-expansion.html http://www.cardiophile.com/2009/09/how-does-mannitol-cause-transient-volume-expansion.html#comments Wed, 16 Sep 2009 00:21:45 +0000 Johnson Francis http://www.cardiophile.com/?p=818 Mannitol being an osmotically active agent draws fluid from the extravascular compartment into the vascular compartment. This causes transient volume expansion and may cause pulmonary edema if the cardiac or renal status is compromised. But if the renal status is good, this extra fluid is soon excreted as mannitol is an osmotic diuretic as well. This property of mannitol is used therapeutically to treat cerebral edema, though caution has to be exercised in those with co-existing renal or cardiac disease.

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